Exosomes hair regeneration using growth factors

Hairsite.com discusses exosomes and their potential in hair loss therapy.

So what are exosomes? Exosomes are the next big thing in stem cell research.

Exosomes are not stem cells per se, but they’re building blocks for stem cells, the functions of these protein building blocks are dependent on their cell of origin. Exosomes are nano-particles involved, in cell-to-cell communication, so think of exosomes as mediators of neighboring cells.

Here’s what Mattias Belting, Professor of Clinical Oncology at Lund University says about exosomes.

“The most exciting thing about exosomes is that they represent a new way of cells to communicate and they can then transfer complex biological information from one cell to another within a particle structure, and as opposed to the current knowledge about how cells communicate through single proteins or single molecules, this is now a whole particle that can carry a lot of complex information between cells. What you’re seeing is actually the green dots are the exosomes that we are isolated. The finding we have, made is done, how these exosomes are received by cells. That is how the exosomes bind to, and make entry into recipient cells.”

There is now mounting evidence that exosomes play an important role in cell to cell communication. Research into exosomes and their viability in the field of regenerative medicine is happening for joint regeneration facial rejuvenation, Lyme disease and even hair regeneration, just to name a few. Exosomes based, there are a pediment, and regenerative medicine research into exosomes for hair restoration, is really starting to recognize the potential of exosomes for people suffering with hair loss.

Presently, exosomes are administered in two ways, for people with hair loss or thinning hair.

The first is an injection after creating a serum, the serum is the same as most blood treatments, but it requires additional filtration and manufacturing to selectively isolate the exosomes. Beneficial growth factors can also be added to the serum at the doctors discretion.

The second delivery method is similar to the first instead of traditional injections, however it adopts a micro-needling technique, and that’s the practice of puncturing the scalp with micro-needles to improve retention and efficacy.

Research by UCLA indicates that both injection and micro-needling are viable although current results suggest that micro-needling may be more effective.

Currently, surgeons are applying exosomes treatment for hair restoration, via injection and that being said, micro-needling may rise in popularity over time or a totally different delivery method may crop up. Exosomes is a brand new cell-based technology and it holds a lot of potential in the field of minimally invasive hair regeneration.